The Female Longevity Advantage

A visionary, evidence-based longevity roadmap built specifically for women’s physiology.

If you’ve ever had ovaries, this book is for you. In The Female Longevity Advantage, regenerative physician Amy Killen, MD, offers a new map for female aging. Drawing on more than two decades of clinical experience, she explains how your ovaries regulate the hormonal system that supports your brain, heart, bones, metabolism, sleep, mood, and sexual health—and offers practical, evidence-informed strategies for protecting that system as it changes.

Inside, you’ll discover:

• The Stack: four evolutionary advantages that power female longevity
• The Perimenopause Pivot: your most critical aging intervention window 
• The HOT Playbook: the latest evidence behind the most misunderstood, underused power tool in women’s longevity, hormone optimization therapy
• The Big O: the overlooked connection between sexual health and longevity
• MENTS: Movement, Environment, Nutrition, Tribe, and Sleep—daily lifestyle practices that actually move the needle

This is not a prescription for chasing youth. It is a guide to understanding your biology, making confident choices, and building the energy, clarity, resilience, and pleasure to thrive through every decade ahead.

• “Most of what we know about longevity was studied in men and then handed to women as if the biology were the same. Amy Killen starts from the opposite premise. The Female Longevity Advantage puts ovarian aging where it belongs, at the center of how women age, and treats hormone therapy as longevity medicine rather than a last resort for hot flashes. A clear, practical, science-grounded resource for any woman who wants to age on her own terms.” 
  Mary Claire Haver, MD, board certified OBGYN
• “Why do women live longer, but suffer longer…? In a world built on male-based research, Dr. Killen dives deep into the science of female physiology with actionable steps all in one place. Personally, I love reading Dr. Killen's work and the wit and thoughtfulness with which she delivers it. I'm confident you will love this book too!” 
  Vonda Wright, MD, orthopaedic sports surgeon, author of Unbreakable
• “The second half of life for women has gotten a bad rap. With The Female Longevity Advantage, Dr. Amy Killen offers a refreshing and much-needed reframe and shows that with the right information and support, the second half of womanhood can be a proactive and empowering experience.” 
  Gabrielle Lyon, MD, author of Forever Young
• “Women live longer than men, yet spend more of those years in poor health. In The Female Longevity Advantage, Dr. Amy Killen brilliantly explains this paradox—and what women can do about it. Empowering, engaging, and essential, this book will help women see their biology not as a burden, but as an extraordinary advantage—and use it to live longer, stronger, and better.” 
  Mark Hyman, MD; Co-Founder, Chief Medical Officer, Function Health; Founder, Cleveland Clinic Center for Functional Medicine
• “For too long, women’s health has been treated as an afterthought. Dr. Amy Killen bridges complex hormone science with practical, actionable strategies, handing women the exact tools we need to take control of our bodies, our future, and our health. This is a paradigm-shifting guide to female longevity.” 
  Jolene Brighten, NMD, FABNE, MSCP, Certified Sex Counselor, author of ADHD and Women, Beyond the Pill, and Is This Normal?
• “Dr. Killen shines a light on the research gaps, the biology of the ovary, hormones, menopause, sexual health, and the innovations that could fundamentally change how women age. This conversation is more important than ever. The future of longevity medicine must include women, not as an afterthought, but as the focus.” 
  Jessica Shepherd, MD, Chief Medical Officer, HERS, author of Generation M
• “Dr. Amy Killen’s female first approach to longevity is a much-needed intervention in the space. I’m proud to have known and learned from Dr. Killen for many years and am thrilled that The Female Longevity Advantage will bring her vital work to the women who need it.” 
  Kayla Barnes-Lentz, founder of The Female Longevity Protocol™ and host of the Brain Biohacking Podcast
• “Forget much of what you’ve been told about women and aging. Amy Killen flips the conventional story on its head, revealing the remarkable biological advantages women already possess and showing how to protect them as hormones change. The Female Longevity Advantage is bold, smart, funny, and packed with actionable advice. Every woman who wants to feel better now and age better for decades to come should read this book.” 
  Frank Lipman, MD, author of Age Better